EZR

GENE INFORMATION

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Gene name

EZR (HGNC Symbol)

Synonyms

VIL2

Description

Ezrin (HGNC Symbol)

Entrez gene summary

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

q25.3

Chromosome location (bp)

158765741 - 158819412

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000092820 (version 78.38)

Entrez gene

7430

UniProt

P15311 (UniProt - Evidence at protein level)

neXtProt

NX_P15311

Antibodypedia

EZR antibodies
 

PROTEIN VIEW

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EZR-001
 
EZR-002
 
EZR-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EZR-001 ENSP00000356042
ENST00000367075
P15311
Show all »
Show » Show » 586 69.4 No 0
EZR-002 ENSP00000338934
ENST00000337147
P15311
Show all »
Show » Show » 586 69.4 No 0
EZR-201 ENSP00000376016
ENST00000392177
B7Z9R6
Show all »
Show » Show » 586 69.4 No 0