CHGA

CANCER ATLAS

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Gene description

Chromogranin A (parathyroid secretory protein 1)

Protein class

Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Carcinoid

STAINING SUMMARY

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HPA017369
 
CAB000023
 
CAB040544
 
CAB055506
 
CAB058688
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Carcinoids and few endometrial cancers along with fraction of cells in few stomach and testicular cancers showed strong cytoplasmic immunoreactivity. Basal cell carcinomas exhibited moderate to strong staining. Remaining cancer tissues were negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected