ABCA2

GENE INFORMATION

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Gene name

ABCA2 (HGNC Symbol)

Synonyms

ABC2

Description

ATP-binding cassette, sub-family A (ABC1), member 2 (HGNC Symbol)

Entrez gene summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

9

Cytoband

q34.3

Chromosome location (bp)

137007227 - 137028922

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107331 (version 78.38)

Entrez gene

20

UniProt

Q9BZC7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BZC7

Antibodypedia

ABCA2 antibodies
 

PROTEIN VIEW

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ABCA2-002
 
ABCA2-022
 
ABCA2-024
 
ABCA2-201
 
ABCA2-202
 
ABCA2-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCA2-002 ENSP00000344155
ENST00000341511
Q9BZC7
Show all »
Show » Show » 2436 269.9 No >9
ABCA2-022 ENSP00000420360
ENST00000490486
H0Y8E3
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Show » 195 21.9 No 0
ABCA2-024 ENSP00000485459
ENST00000625103
Show » 122 13.6 No 1
ABCA2-201 ENSP00000265662
ENST00000265662
B4DI99
Show all »
Show » Show » 2436 269.9 No >9
ABCA2-202 ENSP00000360666
ENST00000371605
Q9BZC7
Show all »
Show » Show » 2435 269.8 No >9
ABCA2-203 ENSP00000481105
ENST00000614293
B4DI99
Show all »
Show » Show » 2466 273 No >9