UBTF

GENE INFORMATION

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Gene name

UBTF (HGNC Symbol)

Synonyms

NOR-90, UBF, UBF1, UBF2

Description

Upstream binding transcription factor, RNA polymerase I (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]

Chromosome

17

Cytoband

q21.31

Chromosome location (bp)

44205033 - 44221626

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000108312 (version 78.38)

Entrez gene

7343

UniProt

P17480 (UniProt - Evidence at protein level)

neXtProt

NX_P17480

Antibodypedia

UBTF antibodies
 

PROTEIN VIEW

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UBTF-001
 
UBTF-002
 
UBTF-004
 
UBTF-005
 
UBTF-006
 
UBTF-007
 
UBTF-008
 
UBTF-009
 
UBTF-011
 
UBTF-014
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UBTF-001 ENSP00000345297
ENST00000343638
P17480
Show all »
Show » Show » 727 84.9 No 0
UBTF-002 ENSP00000302640
ENST00000302904
P17480
Show all »
Show » Show » 764 89.4 No 0
UBTF-004 ENSP00000377231
ENST00000393606
P17480
Show all »
Show » Show » 727 84.9 No 0
UBTF-005 ENSP00000390669
ENST00000436088
P17480
Show all »
Show » Show » 764 89.4 No 0
UBTF-006 ENSP00000437180
ENST00000533177
P17480
Show all »
Show » Show » 727 84.9 No 0
UBTF-007 ENSP00000432925
ENST00000526094
P17480
Show all »
Show » Show » 727 84.9 No 0
UBTF-008 ENSP00000435708
ENST00000529383
P17480
Show all »
Show » Show » 764 89.4 No 0
UBTF-009 ENSP00000433046
ENST00000530828
E9PMM2
Show all »
Show » 149 17.8 No 0
UBTF-011 ENSP00000431295
ENST00000529373
E9PLT2
Show all »
Show » 194 23 No 0
UBTF-014 ENSP00000431539
ENST00000527034
E9PKP7
Show all »
Show » Show » 745 87.4 No 0