Splice variant |
Ensembl |
UniProt |
Protein class |
Gene ontology |
Length (aa) |
Molecular mass (kDa) |
Signal peptide (predicted) |
Transmembrane regions (predicted)
|
OPRM1-001 |
ENSP00000328264
ENST00000330432
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P35372 Show all »
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P35372 [Direct mapping]Mu-type opioid receptor C7E9I8 [Target identity:74%; Query identity:100%]Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313|EMBL:ACT35692.1} Q71V90 [Target identity:68%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} B8K2Q5 [Target identity:28%; Query identity:100%]Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1} C9E9Z9 [Target identity:24%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1} C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1} Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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400 |
44.8 |
No |
7 |
OPRM1-002 |
ENSP00000411903
ENST00000428397
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P35372 Show all »
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P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:70%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} B8K2Q5 [Target identity:29%; Query identity:100%]Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1} C9E9Z9 [Target identity:24%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1} C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1} Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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392 |
44 |
No |
7 |
OPRM1-003 |
ENSP00000394624
ENST00000434900
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P35372 Show all »
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P35372 [Direct mapping]Mu-type opioid receptor C7E9I8 [Target identity:60%; Query identity:100%]Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313|EMBL:ACT35692.1} Q71V90 [Target identity:55%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} B8K2Q5 [Target identity:23%; Query identity:100%]Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1} C9E9Z9 [Target identity:19%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1} C9EA00 [Target identity:19%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1} Q7Z6A5 [Target identity:8%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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493 |
55 |
No |
7 |
OPRM1-004 |
ENSP00000430247
ENST00000520282
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E7EW71 Show all »
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E7EW71 [Target identity:99%; Query identity:100%]Mu-type opioid receptor {ECO:0000313|Ensembl:ENSP00000430247} B8K2Q5 [Target identity:70%; Query identity:100%]Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1} C9E9Z9 [Target identity:58%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1} C9EA00 [Target identity:57%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1}
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Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM
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163 |
17.3 |
No |
1 |
OPRM1-005 |
ENSP00000430876
ENST00000520708
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P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor C7E9I8 [Target identity:99%; Query identity:100%]Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313|EMBL:ACT35692.1} Q71V90 [Target identity:91%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} Q7Z6A5 [Target identity:13%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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300 |
34.4 |
No |
6 |
OPRM1-006 |
ENSP00000430260
ENST00000518759
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P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor C7E9I8 [Target identity:93%; Query identity:100%]Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313|EMBL:ACT35692.1} Q71V90 [Target identity:86%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} Q7Z6A5 [Target identity:12%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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319 |
36.5 |
No |
5 |
OPRM1-008 |
ENSP00000338381
ENST00000337049
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P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:65%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} B8K2Q5 [Target identity:27%; Query identity:100%]Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1} C9E9Z9 [Target identity:22%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1} C9EA00 [Target identity:22%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1} Q7Z6A5 [Target identity:9%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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418 |
47 |
No |
7 |
OPRM1-010 |
ENSP00000410497
ENST00000452687
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P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:67%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} B8K2Q5 [Target identity:28%; Query identity:100%]Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1} C9E9Z9 [Target identity:23%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1} C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1} Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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406 |
45.5 |
No |
7 |
OPRM1-012 |
ENSP00000229768
ENST00000229768
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P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:61%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} B8K2Q5 [Target identity:25%; Query identity:100%]Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1} C9E9Z9 [Target identity:21%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1} C9EA00 [Target identity:21%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1} Q7Z6A5 [Target identity:9%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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« Hide
GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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446 |
49.5 |
No |
7 |
OPRM1-013 |
ENSP00000403549
ENST00000419506
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P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:65%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} B8K2Q5 [Target identity:27%; Query identity:100%]Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1} C9E9Z9 [Target identity:22%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1} C9EA00 [Target identity:22%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1} Q7Z6A5 [Target identity:9%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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420 |
47.1 |
No |
7 |
OPRM1-014 |
ENSP00000430097
ENST00000524163
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P35372 Show all »
« Hide
P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:70%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} B8K2Q5 [Target identity:29%; Query identity:100%]Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1} C9E9Z9 [Target identity:24%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1} C9EA00 [Target identity:24%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1} Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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389 |
43.6 |
No |
7 |
OPRM1-016 |
ENSP00000399359
ENST00000414028
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P35372 Show all »
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P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:68%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} B8K2Q5 [Target identity:28%; Query identity:100%]Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1} C9E9Z9 [Target identity:23%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1} C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1} Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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403 |
44.9 |
No |
7 |
OPRM1-017 |
ENSP00000413752
ENST00000435918
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P35372 Show all »
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P35372 [Direct mapping]Mu-type opioid receptor Q71V90 [Target identity:69%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} B8K2Q5 [Target identity:28%; Query identity:100%]Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1} C9E9Z9 [Target identity:24%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1} C9EA00 [Target identity:23%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1} Q7Z6A5 [Target identity:10%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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397 |
44.7 |
No |
7 |
OPRM1-019 |
ENSP00000429719
ENST00000522555
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P35372 Show all »
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P35372 [Direct mapping]Mu-type opioid receptor C7E9I8 [Target identity:99%; Query identity:100%]Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313|EMBL:ACT35692.1} Q71V90 [Target identity:91%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} Q7Z6A5 [Target identity:13%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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300 |
34.4 |
No |
6 |
OPRM1-020 |
ENSP00000429373
ENST00000522236
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P35372 Show all »
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P35372 [Direct mapping]Mu-type opioid receptor C7E9I8 [Target identity:99%; Query identity:100%]Opioid receptor mu 1 transcript variant hMOR-1JL {ECO:0000313|EMBL:ACT35692.1} Q71V90 [Target identity:91%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} Q7Z6A5 [Target identity:13%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM FDA approved drug targets Small molecule drugs
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GO:0001965 [G-protein alpha-subunit binding] GO:0004930 [G-protein coupled receptor activity] GO:0004979 [beta-endorphin receptor activity] GO:0005245 [voltage-gated calcium channel activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007187 [G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger] GO:0007194 [negative regulation of adenylate cyclase activity] GO:0007200 [phospholipase C-activating G-protein coupled receptor signaling pathway] GO:0007204 [positive regulation of cytosolic calcium ion concentration] GO:0007218 [neuropeptide signaling pathway] GO:0007600 [sensory perception] GO:0008285 [negative regulation of cell proliferation] GO:0016021 [integral component of membrane] GO:0019233 [sensory perception of pain] GO:0033554 [cellular response to stress] GO:0038003 [opioid receptor signaling pathway] GO:0038047 [morphine receptor activity] GO:0043950 [positive regulation of cAMP-mediated signaling] GO:0043951 [negative regulation of cAMP-mediated signaling] GO:0045019 [negative regulation of nitric oxide biosynthetic process] GO:0045429 [positive regulation of nitric oxide biosynthetic process] GO:0048149 [behavioral response to ethanol] GO:0050769 [positive regulation of neurogenesis] GO:0051481 [negative regulation of cytosolic calcium ion concentration] GO:0061358 [negative regulation of Wnt protein secretion] GO:0070374 [positive regulation of ERK1 and ERK2 cascade] GO:0070588 [calcium ion transmembrane transport] GO:2000310 [regulation of N-methyl-D-aspartate selective glutamate receptor activity]
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300 |
34.4 |
No |
6 |
OPRM1-201 |
ENSP00000353598
ENST00000360422
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L0E130 Show all »
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L0E130 [Target identity:100%; Query identity:100%]Micro opioid receptor isoform hMOR-1A2 {ECO:0000313|EMBL:AGA35553.1} Q71V90 [Target identity:57%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAC51878.1} B8K2Q5 [Target identity:24%; Query identity:100%]Mu opioid receptor splice variant MOR-1H {ECO:0000313|EMBL:ABH03503.1} C9E9Z9 [Target identity:20%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85685.1} C9EA00 [Target identity:19%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:ACV85686.1} Q7Z6A5 [Target identity:8%; Query identity:100%]Mu opioid receptor {ECO:0000313|EMBL:AAP58255.1}
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Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM
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476 |
53.3 |
No |
7 |