SMAD5

GENE INFORMATION

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Gene name

SMAD5 (HGNC Symbol)

Synonyms

Dwfc, JV5-1, MADH5

Description

SMAD family member 5 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is involved in the transforming growth factor beta signaling pathway that results in an inhibition of the proliferation of hematopoietic progenitor cells. The encoded protein is activated by bone morphogenetic proteins type 1 receptor kinase, and may be involved in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Chromosome

5

Cytoband

q31.1

Chromosome location (bp)

136132845 - 136188747

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000113658 (version 78.38)

Entrez gene

4090

UniProt

Q99717 (UniProt - Evidence at protein level)

neXtProt

NX_Q99717

Antibodypedia

SMAD5 antibodies
 

PROTEIN VIEW

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SMAD5-001
 
SMAD5-002
 
SMAD5-003
 
SMAD5-004
 
SMAD5-005
 
SMAD5-008
 
SMAD5-010
 
SMAD5-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SMAD5-001 ENSP00000441954
ENST00000545279
Q99717
Show all »
Show » Show » 465 52.3 No 0
SMAD5-002 ENSP00000425749
ENST00000507118
D6RIZ9
Show all »
Show » Show » 128 14.7 No 0
SMAD5-003 ENSP00000424279
ENST00000511116
D6RBB4
Show all »
Show » Show » 134 15.4 No 0
SMAD5-004 ENSP00000426696
ENST00000509297
Show » 1 0.1 No 0
SMAD5-005 ENSP00000427330
ENST00000515005
Show » 1 0.1 No 0
SMAD5-008 ENSP00000422954
ENST00000506223
D6R9D4
Show all »
Show » Show » 80 8.8 No 0
SMAD5-010 ENSP00000427474
ENST00000507637
Show » Show » 174 19.1 No 0
SMAD5-201 ENSP00000446474
ENST00000545620
Q99717
Show all »
Show » Show » 465 52.3 No 0