PKD2

CANCER ATLAS

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Gene description

Polycystic kidney disease 2 (autosomal dominant)

Protein class

Disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Renal cancer

STAINING SUMMARY

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HPA015794
 
CAB004544
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Malignant cells generally displayed weak to moderate cytoplasmic staining. Staining in luminal membranes was observed in a number of cancers for example, colorectal, endometrial and liver. Occasional strongly stained cases were observed among malignant melanomas and urothelial cancers. Skin and testicular tumors were negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected