MRPS7

GENE INFORMATION

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Gene name

MRPS7 (HGNC Symbol)

Synonyms

MRP-S, RP-S7, RPMS7

Description

Mitochondrial ribosomal protein S7 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. In the prokaryotic ribosome, the comparable protein is thought to play an essential role in organizing the 3' domain of the 16 S rRNA in the vicinity of the P- and A-sites. Pseudogenes corresponding to this gene are found on chromosomes 8p and 12p. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q25.1

Chromosome location (bp)

75261674 - 75266373

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000125445 (version 78.38)

Entrez gene

51081

UniProt

Q9Y2R9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y2R9

Antibodypedia

MRPS7 antibodies
 

PROTEIN VIEW

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MRPS7-001
 
MRPS7-002
 
MRPS7-003
 
MRPS7-005
 
MRPS7-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS7-001 ENSP00000245539
ENST00000245539
Q9Y2R9
Show all »
Show » Show » 242 28.1 No 0
MRPS7-002 ENSP00000463263
ENST00000579761
J3QKW2
Show all »
Show » Show » 183 20.8 No 0
MRPS7-003 ENSP00000463683
ENST00000579002
J3QLS3
Show all »
Show » Show » 271 31.7 No 0
MRPS7-005 ENSP00000463870
ENST00000581993
Q96Q63
Show all »
Show » 172 19.9 No 0
MRPS7-006 ENSP00000462506
ENST00000584678
Q96Q63
Show all »
Show » 156 18.3 No 0