GALNT8

GENE INFORMATION

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Gene name

GALNT8 (HGNC Symbol)

Synonyms

GALNAC-T8

Description

Polypeptide N-acetylgalactosaminyltransferase 8 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. [provided by RefSeq, Jul 2008]

Chromosome

12

Cytoband

p13.32

Chromosome location (bp)

4720341 - 4851927

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000130035 (version 78.38)

Entrez gene

26290

UniProt

Q9NY28 (UniProt - Evidence at transcript level), P17658 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NY28, NX_P17658

Antibodypedia

GALNT8 antibodies
 

PROTEIN VIEW

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GALNT8-001
 
GALNT8-002
 
GALNT8-004
 
GALNT8-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GALNT8-001 ENSP00000252318
ENST00000252318
Q9NY28
Show all »
Show » Show » 637 72.9 Yes 0
GALNT8-002 ENSP00000440383
ENST00000542998
Show » 161 18.1 No 0
GALNT8-004 ENSP00000444876
ENST00000535354
Show » 88 9.8 No 0
GALNT8-201 ENSP00000408321
ENST00000433855
P17658
Show all »
Show » Show » 529 58.7 No 5