PPP1R1B

GENE INFORMATION

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Gene name

PPP1R1B (HGNC Symbol)

Synonyms

DARPP-32, FLJ20940

Description

Protein phosphatase 1, regulatory (inhibitor) subunit 1B (HGNC Symbol)

Entrez gene summary

This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Chromosome

17

Cytoband

q12

Chromosome location (bp)

39626740 - 39636626

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000131771 (version 78.38)

Entrez gene

84152

UniProt

Q9UD71 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UD71

Antibodypedia

PPP1R1B antibodies
 

PROTEIN VIEW

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PPP1R1B-001
 
PPP1R1B-002
 
PPP1R1B-005
 
PPP1R1B-008
 
PPP1R1B-013
 
PPP1R1B-014
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPP1R1B-001 ENSP00000254079
ENST00000254079
Q9UD71
Show all »
Show » Show » 204 23 No 0
PPP1R1B-002 ENSP00000377810
ENST00000394267
Q9UD71
Show all »
Show » Show » 168 18.7 No 0
PPP1R1B-005 ENSP00000377808
ENST00000394265
Q9UD71
Show all »
Show » Show » 168 18.7 No 0
PPP1R1B-008 ENSP00000462841
ENST00000579000
J3KT77
Show all »
Show » Show » 171 19.3 No 0
PPP1R1B-013 ENSP00000462137
ENST00000580825
Q9UD71
Show all »
Show » Show » 204 23 No 0
PPP1R1B-014 ENSP00000462522
ENST00000582680
J3KSJ8
Show all »
Show » Show » 145 16.7 No 0