IRS4

GENE INFORMATION

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Gene name

IRS4 (HGNC Symbol)

Synonyms

IRS-4, PY160

Description

Insulin receptor substrate 4 (HGNC Symbol)

Entrez gene summary

IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

q22.3

Chromosome location (bp)

108732482 - 108736409

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000133124 (version 78.38)

Entrez gene

8471

UniProt

O14654 (UniProt - Evidence at protein level)

neXtProt

NX_O14654

Antibodypedia

IRS4 antibodies
 

PROTEIN VIEW

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IRS4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IRS4-001 ENSP00000361202
ENST00000372129
O14654
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