SMAD6

GENE INFORMATION

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Gene name

SMAD6 (HGNC Symbol)

Synonyms

HsT17432, MADH6, MADH7

Description

SMAD family member 6 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.[provided by RefSeq, Sep 2014]

Chromosome

15

Cytoband

q22.31

Chromosome location (bp)

66702228 - 66782848

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000137834 (version 78.38)

Entrez gene

4091

UniProt

O43541 (UniProt - Evidence at protein level)

neXtProt

NX_O43541

Antibodypedia

SMAD6 antibodies
 

PROTEIN VIEW

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SMAD6-001
 
SMAD6-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SMAD6-001 ENSP00000288840
ENST00000288840
O43541
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Show » Show » 496 53.5 No 0
SMAD6-004 ENSP00000452694
ENST00000558937
H0YK80
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Show » 55 5.8 No 0