The primary data page shows the detailed antibody staining in 83 different cell types for each analyzed antibody
and in cases where a knowledge-based annotated protein expression profile is available, this
result is displayed in an additional column to the right. The level of expression is also given by a blue-scale
color-coding (described by the scale in the box to the right). More detailed information can be found under
Assays & annotation. The antibodies analyzed are listed in the "Antibodies in assay"-field.
The tissues and cell types can be ordered by organ, cell type or alphabetically. The organ view displays the representative
tissues organized in tissue groups according to functional features or anatomical location. The cell type view displays the
representative tissues organized in groups related to origin. The view allows the viewer to identify cell type specific
patterns of expression e.g. CD20 expression in hematopoietic cell types.
For each tissue and cell type, the antibody staining is given with the blue-scale color-coding (described by the scale
in the box to the right). Each available antibody is listed in a separate column and the antibody identifier is available
at the bottom of the tissue list. The images and annotations can be accessed by clicking on the tissue name.
Enteroendocrine cells in the gastrointestinal tract along with islet cells in pancreas, parathyroid and adrenal gland exhibited strong immunoreactivity. Normal tissues generally showed weak to moderate cytoplasmic positivity. The intestinal tract showed strong membranous positivity. Skeletal muscle was strongly stained.
Normal tissues generally showed moderate cytoplasmic and nuclear staining. Stomach and subsets of neuronal cells exhibited strong cytoplasmic and nuclear immunoreactivity while lung macrophages displayed strong cytoplasmic staining. Renal glomeruli and smooth muscle cells were negative.
Level of antibody staining/expression
High Medium Low Not detected
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.