MRPL39

GENE INFORMATION

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Gene name

MRPL39 (HGNC Symbol)

Synonyms

C21orf92, FLJ20451, L39mt, MGC104174, MGC3400, MRP-L5, MSTP003, PRED22, PRED66, RPML5

Description

Mitochondrial ribosomal protein L39 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Jul 2008]

Chromosome

21

Cytoband

q21.3

Chromosome location (bp)

25585656 - 25607517

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000154719 (version 78.38)

Entrez gene

54148

UniProt

Q9NYK5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NYK5

Antibodypedia

MRPL39 antibodies
 

PROTEIN VIEW

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MRPL39-001
 
MRPL39-002
 
MRPL39-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL39-001 ENSP00000284967
ENST00000352957
Q9NYK5
Show all »
Show » Show » 338 38.7 No 0
MRPL39-002 ENSP00000305682
ENST00000307301
Q9NYK5
Show all »
Show » Show » 353 40.5 No 0
MRPL39-003 ENSP00000404426
ENST00000419219
C9JG87
Show all »
Show » Show » 297 34 No 0