MRPL17

GENE INFORMATION

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Gene name

MRPL17 (HGNC Symbol)

Synonyms

MRP-L26, RPML26

Description

Mitochondrial ribosomal protein L17 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

p15.4

Chromosome location (bp)

6680782 - 6683401

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000158042 (version 78.38)

Entrez gene

63875

UniProt

Q9NRX2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NRX2

Antibodypedia

MRPL17 antibodies
 

PROTEIN VIEW

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MRPL17-001
 
MRPL17-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL17-001 ENSP00000288937
ENST00000288937
Q9NRX2
Show all »
Show » Show » 175 20.1 No 0
MRPL17-004 ENSP00000435294
ENST00000532203
E9PKV2
Show all »
Show » Show » 142 16.4 No 0