NEK8

CANCER ATLAS

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Gene description

NIMA-related kinase 8

Protein class

Cytoskeleton related proteins, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

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HPA040661
 
 
HPA040679
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Many cases of colorectal cancers along with a few cases of liver, gastric, renal, testicular, prostate and cervical cancers displayed moderate cytoplasmic positivity with additional membranous or nuclear staining in occasional cases. Remaining malignant cells were weakly stained or generally negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected