EIF4EBP1

CANCER ATLAS

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Gene description

Eukaryotic translation initiation factor 4E binding protein 1

Protein class

Cancer-related genes, Predicted intracellular proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

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HPA023501
 
CAB005032
 
CAB005039
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Malignant cells showed moderate to strong cytoplasmic and nuclear staining. Malignant melanomas, prostate and colorectal cancers displayed moderate to strong cytoplasmic staining with an additional nuclear immunoreactivity. A few cases of skin cancers displayed strong cytoplasmic staining. Most tumors of female genital tract, pancreatic and lung cancers showed moderate cytoplasmic and nuclear staining. Malignant gliomas and liver cancers were generally negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected