PLEKHH1

CANCER ATLAS

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Gene description

Pleckstrin homology domain containing, family H (with MyTH4 domain) member 1

Protein class

Cytoskeleton related proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

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HPA047707
 
HPA051964
 

Tissue

Cancer staining

Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma
 

Tissue

Cancer staining

Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer
 

Staining summary

Single cases of duct carcinoma of breast, pancreatic cancer and low grade gliomas displayed moderate cytoplasmic immunoreactivity. A fraction of cells in a few renal cancers displayed nuclear positivity. Other cells were generally negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected