DGCR6

CANCER ATLAS

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Gene description

DiGeorge syndrome critical region gene 6

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

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HPA047905
 

Tissue

Cancer staining

Normal tissue
staining

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Normal tissue
staining

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

A few adenocarcinomas of lung and stomach cancers showed moderate to strong cytoplasmic staining along with distinct extracellular positivity, while malignant melanomas and ovarian cancers exhibited moderate positivity. A few colorectal cancers displayed moderate cytoplasmic, membranous and nuclear staining. Several cases of pancreatic cancers displayed moderate to strong cytoplasmic and nuclear staining while liver cancers exhibited moderate immunoreactivity. Remaining cancer tissues were weakly stained or negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected