IGSF23

CANCER ATLAS

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Gene description

Immunoglobulin superfamily, member 23

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at transcript level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

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HPA051811
 
 
HPA054591
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Few cases of squamous cell carcinomas of cervix, renal, liver cancers and a single case of urothelial cancer showed moderate to strong membranous staining. Prostate and skin cancers displayed moderate cytoplasmic staining while a single case of follicular adenocarcinoma displayed strong positivity. Several cases of melanomas exhibited moderate cytoplasmic and membranous immunoreactivity. Remaining cancer tissues were negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected