TNMD

GENE INFORMATION

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Gene name

TNMD (HGNC Symbol)

Synonyms

BRICD4, ChM1L, myodulin, TEM, tendin

Description

Tenomodulin (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009]

Chromosome

X

Cytoband

q22.1

Chromosome location (bp)

100584802 - 100599885

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000000005 (version 78.38)

Entrez gene

64102

UniProt

Q9H2S6 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9H2S6

Antibodypedia

TNMD antibodies
 

PROTEIN VIEW

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TNMD-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TNMD-001 ENSP00000362122
ENST00000373031
Q9H2S6
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