LASP1

GENE INFORMATION

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Gene name

LASP1 (HGNC Symbol)

Synonyms

Lasp-1, MLN50

Description

LIM and SH3 protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012]

Chromosome

17

Cytoband

q12

Chromosome location (bp)

38869859 - 38921770

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000002834 (version 78.38)

Entrez gene

3927

UniProt

Q14847 (UniProt - Evidence at protein level)

neXtProt

NX_Q14847

Antibodypedia

LASP1 antibodies
 

PROTEIN VIEW

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LASP1-001
 
LASP1-002
 
LASP1-008
 
LASP1-201
 
LASP1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LASP1-001 ENSP00000325240
ENST00000318008
Q14847
Show all »
Show » Show » 261 29.7 No 0
LASP1-002 ENSP00000391897
ENST00000419929
C9J9W2
Show all »
Show » 166 19 No 0
LASP1-008 ENSP00000462564
ENST00000579123
J3KSN1
Show all »
Show » 105 11.4 No 0
LASP1-201 ENSP00000401048
ENST00000433206
Q14847
Show all »
Show » Show » 205 23.2 No 0
LASP1-202 ENSP00000392853
ENST00000435347
Q14847
Show all »
Show » Show » 261 29.7 No 0