M6PR

GENE INFORMATION

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Gene name

M6PR

Synonyms

Description

Mannose-6-phosphate receptor (cation dependent) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011]

Chromosome

12

Cytoband

p13.31

Chromosome location (bp)

8940363 - 8949955

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000003056 (version 78.38)

Entrez gene

4074

UniProt

P20645 (UniProt - Evidence at protein level)

neXtProt

NX_P20645

Antibodypedia

M6PR antibodies
 

PROTEIN VIEW

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M6PR-001
 
M6PR-003
 
M6PR-004
 
M6PR-005
 
M6PR-009
 
M6PR-010
 
M6PR-011
 
M6PR-012
 
M6PR-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

M6PR-001 ENSP00000000412
ENST00000000412
P20645
Show all »
Show » Show » 277 31 Yes 1
M6PR-003 ENSP00000439968
ENST00000544245
F5H4U1
Show all »
Show » 25 2.9 No 0
M6PR-004 ENSP00000440962
ENST00000543845
F5GXU0
Show all »
Show » Show » 109 12.2 Yes 0
M6PR-005 ENSP00000441030
ENST00000543159
F5GXE0
Show all »
Show » Show » 92 10.4 Yes 0
M6PR-009 ENSP00000444684
ENST00000537621
Show » 122 13.3 No 1
M6PR-010 ENSP00000439070
ENST00000539143
Show » 96 10.3 No 0
M6PR-011 ENSP00000437595
ENST00000543704
H0YF90
Show all »
Show » Show » 148 16.4 Yes 1
M6PR-012 ENSP00000441040
ENST00000544193
H0YFY9
Show all »
Show » 85 9.4 No 1
M6PR-201 ENSP00000440488
ENST00000536844
F5GXU0
Show all »
Show » Show » 191 21.5 Yes 0