ITGA3

GENE INFORMATION

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Gene name

ITGA3 (HGNC Symbol)

Synonyms

CD49c, GAP-B3, MSK18, VCA-2, VLA3a

Description

Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the family of integrins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain, and function as cell surface adhesion molecules. This gene encodes alpha 3 subunit, which undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 subunit to form an integrin that interacts with many extracellular-matrix proteins. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008]

Chromosome

17

Cytoband

q21.33

Chromosome location (bp)

50055968 - 50090481

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000005884 (version 78.38)

Entrez gene

3675

UniProt

P26006 (UniProt - Evidence at protein level)

neXtProt

NX_P26006

Antibodypedia

ITGA3 antibodies
 

PROTEIN VIEW

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ITGA3-001
 
ITGA3-010
 
ITGA3-014
 
ITGA3-020
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ITGA3-001 ENSP00000315190
ENST00000320031
P26006
Show all »
Show » Show » 1051 116.6 Yes 1
ITGA3-010 ENSP00000466652
ENST00000512553
K7EMU3
Show all »
Show » Show » 117 12.9 No 0
ITGA3-014 ENSP00000426142
ENST00000506827
Show » 221 24.6 No 0
ITGA3-020 ENSP00000007722
ENST00000007722
P26006
Show all »
Show » Show » 1066 118.8 Yes 1