MAP3K14

GENE INFORMATION

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Gene name

MAP3K14 (HGNC Symbol)

Synonyms

FTDCR1B, HS, HSNIK, NIK

Description

Mitogen-activated protein kinase kinase kinase 14 (HGNC Symbol)

Entrez gene summary

This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.31

Chromosome location (bp)

45263121 - 45317040

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000006062 (version 78.38)

Entrez gene

9020

UniProt

Q99558 (UniProt - Evidence at protein level)

neXtProt

NX_Q99558

Antibodypedia

MAP3K14 antibodies
 

PROTEIN VIEW

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MAP3K14-001
 
MAP3K14-005
 
MAP3K14-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAP3K14-001 ENSP00000478552
ENST00000344686
Q99558
Show all »
Show » Show » 947 104 No 0
MAP3K14-005 ENSP00000480974
ENST00000617331
Show » 157 17.1 No 0
MAP3K14-201 ENSP00000482657
ENST00000376926
Q99558
Show all »
Show » Show » 947 104 No 0