IFRD1 - Gene info - The Human Protein Atlas

IFRD1

TISSUE

SUBCELL

CELL LINE

CANCER

GENE INFORMATION

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Gene name	IFRD1 (HGNC Symbol)
Synonyms	PC4, TIS7
Description	Interferon-related developmental regulator 1 (HGNC Symbol)
Entrez gene summary	This gene is an immediate early gene that encodes a protein related to interferon-gamma. This protein may function as a transcriptional co-activator/repressor that controls the growth and differentiation of specific cell types during embryonic development and tissue regeneration. Mutations in this gene are associated with sensory/motor neuropathy with ataxia. This gene may also be involved in modulating the pathogenesis of cystic fibrosis lung disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]
Chromosome	7
Cytoband	q31.1
Chromosome location (bp)	112422968 - 112481017
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000006652 (version 78.38)
Entrez gene	3475
UniProt	O00458 (UniProt - Evidence at protein level)
neXtProt	NX_O00458
Antibodypedia	IFRD1 antibodies

PROTEIN VIEW

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IFRD1-001		IFRD1-002		IFRD1-003		IFRD1-005		IFRD1-006		IFRD1-007		IFRD1-008		IFRD1-009		IFRD1-011		IFRD1-013		IFRD1-014		IFRD1-201		IFRD1-202

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)	Transmembrane regions (predicted)
IFRD1-001	ENSP00000005558 ENST00000005558	O00458 Show all » « Hide O00458 [Direct mapping] Interferon-related developmental regulator 1 A4D0U1 [Target identity:100%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|EMBL:EAL24375.1}; Interferon-related developmental regulator 1, isoform CRA_a {ECO:0000313\|EMBL:EAW83462.1} Q75MS4 [Target identity:54%; Query identity:100%] Putative uncharacterized protein IFRD1 {ECO:0000313\|EMBL:AAS07421.1} Q75M99 [Target identity:45%; Query identity:100%] Putative uncharacterized protein IFRD1 {ECO:0000313\|EMBL:AAS02003.1} Q75M98 [Target identity:41%; Query identity:100%] Putative uncharacterized protein IFRD1 {ECO:0000313\|EMBL:AAS02004.1} B7Z4L0 [Target identity:34%; Query identity:100%] cDNA FLJ54027, highly similar to Interferon-related developmental regulator 1 {ECO:0000313\|EMBL:BAH12596.1} C9JNM6 [Target identity:28%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000402177} E9PMY4 [Target identity:22%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000437250} C9JFH1 [Target identity:19%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000403203} C9JLG5 [Target identity:13%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000402453} C9J7U6 [Target identity:8%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000397592} C9J311 [Target identity:6%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000391379}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0005488 [binding] GO:0007275 [multicellular organismal development] GO:0007518 [myoblast fate determination]	451	50.3	No	1
IFRD1-002	ENSP00000384477 ENST00000403825	O00458 Show all » « Hide O00458 [Direct mapping] Interferon-related developmental regulator 1 A4D0U1 [Target identity:100%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|EMBL:EAL24375.1}; Interferon-related developmental regulator 1, isoform CRA_a {ECO:0000313\|EMBL:EAW83462.1} Q75MS4 [Target identity:54%; Query identity:100%] Putative uncharacterized protein IFRD1 {ECO:0000313\|EMBL:AAS07421.1} Q75M99 [Target identity:45%; Query identity:100%] Putative uncharacterized protein IFRD1 {ECO:0000313\|EMBL:AAS02003.1} Q75M98 [Target identity:41%; Query identity:100%] Putative uncharacterized protein IFRD1 {ECO:0000313\|EMBL:AAS02004.1} B7Z4L0 [Target identity:34%; Query identity:100%] cDNA FLJ54027, highly similar to Interferon-related developmental regulator 1 {ECO:0000313\|EMBL:BAH12596.1} C9JNM6 [Target identity:28%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000402177} E9PMY4 [Target identity:22%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000437250} C9JFH1 [Target identity:19%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000403203} C9JLG5 [Target identity:13%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000402453} C9J7U6 [Target identity:8%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000397592} C9J311 [Target identity:6%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000391379}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0005488 [binding] GO:0005634 [nucleus] GO:0007275 [multicellular organismal development] GO:0007518 [myoblast fate determination] GO:0007527 [adult somatic muscle development] GO:0042692 [muscle cell differentiation]	451	50.3	No	1
IFRD1-003	ENSP00000397314 ENST00000429071	C9JA65 Show all » « Hide C9JA65 [Target identity:100%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000397314} C9JLG5 [Target identity:41%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000402453} C9J7U6 [Target identity:27%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000397592} C9J311 [Target identity:20%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000391379}	Show » « Hide SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		148	15.9	No	0
IFRD1-005	ENSP00000397592 ENST00000443101	C9J7U6 Show all » « Hide C9J7U6 [Target identity:100%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000397592}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		40	4.4	No	0
IFRD1-006	ENSP00000402453 ENST00000445335	C9JLG5 Show all » « Hide C9JLG5 [Target identity:100%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000402453} C9J311 [Target identity:48%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000391379}	Show » « Hide SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		62	6.2	No	0
IFRD1-007	ENSP00000413893 ENST00000417662		Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		18	1.9	No	0
IFRD1-008	ENSP00000437250 ENST00000476927	E9PMY4 Show all » « Hide E9PMY4 [Target identity:100%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000437250} C9J7U6 [Target identity:38%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000397592}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		103	11.3	No	0
IFRD1-009	ENSP00000402177 ENST00000440625	C9JNM6 Show all » « Hide C9JNM6 [Target identity:100%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000402177} E9PMY4 [Target identity:81%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000437250} C9J7U6 [Target identity:31%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000397592}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0005488 [binding]	127	13.9	No	0
IFRD1-011	ENSP00000403203 ENST00000421296	C9JFH1 Show all » « Hide C9JFH1 [Target identity:100%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000403203}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		90	10.4	No	0
IFRD1-013	ENSP00000435635 ENST00000462155	H0YEE3 Show all » « Hide H0YEE3 [Target identity:100%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000435635}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		98	11.4	No	0
IFRD1-014	ENSP00000391379 ENST00000432734	C9J311 Show all » « Hide C9J311 [Target identity:96%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000391379}	Show » « Hide SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)		31	2.9	No	0
IFRD1-201	ENSP00000439188 ENST00000535603	O00458 Show all » « Hide O00458 [Direct mapping] Interferon-related developmental regulator 1 Q75MS4 [Target identity:61%; Query identity:100%] Putative uncharacterized protein IFRD1 {ECO:0000313\|EMBL:AAS07421.1} B7Z4L0 [Target identity:39%; Query identity:100%] cDNA FLJ54027, highly similar to Interferon-related developmental regulator 1 {ECO:0000313\|EMBL:BAH12596.1} C9JNM6 [Target identity:31%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000402177} E9PMY4 [Target identity:25%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000437250} C9JFH1 [Target identity:22%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000403203} C9J7U6 [Target identity:9%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000397592}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0005488 [binding] GO:0007275 [multicellular organismal development] GO:0007518 [myoblast fate determination]	401	45.3	No	1
IFRD1-202	ENSP00000483255 ENST00000621379	O00458 Show all » « Hide O00458 [Direct mapping] Interferon-related developmental regulator 1 Q75MS4 [Target identity:61%; Query identity:100%] Putative uncharacterized protein IFRD1 {ECO:0000313\|EMBL:AAS07421.1} B7Z4L0 [Target identity:39%; Query identity:100%] cDNA FLJ54027, highly similar to Interferon-related developmental regulator 1 {ECO:0000313\|EMBL:BAH12596.1} C9JNM6 [Target identity:31%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000402177} E9PMY4 [Target identity:25%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000437250} C9JFH1 [Target identity:22%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000403203} C9J7U6 [Target identity:9%; Query identity:100%] Interferon-related developmental regulator 1 {ECO:0000313\|Ensembl:ENSP00000397592}	Show » « Hide Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)	Show » « Hide GO:0005488 [binding] GO:0007275 [multicellular organismal development] GO:0007518 [myoblast fate determination]	401	45.3	No	1

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.