NOS2

GENE INFORMATION

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Gene name

NOS2 (HGNC Symbol)

Synonyms

HEP-NOS, iNOS, NOS, NOS2A

Description

Nitric oxide synthase 2, inducible (HGNC Symbol)

Entrez gene summary

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q11.2

Chromosome location (bp)

27756766 - 27800499

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000007171 (version 78.38)

Entrez gene

4843

UniProt

P35228 (UniProt - Evidence at protein level)

neXtProt

NX_P35228

Antibodypedia

NOS2 antibodies
 

PROTEIN VIEW

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NOS2-001
 
NOS2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NOS2-001 ENSP00000327251
ENST00000313735
P35228
Show all »
Show » Show » 1153 131.1 No 0
NOS2-201 ENSP00000482291
ENST00000621962
P35228
Show all »
Show » Show » 1114 126.7 No 0