SYN1

GENE INFORMATION

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Gene name

SYN1

Synonyms

Description

Synapsin I (HGNC Symbol)

Entrez gene summary

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

Chromosome location (bp)

47571898 - 47619853

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000008056 (version 78.38)

Entrez gene

6853

UniProt

P17600 (UniProt - Evidence at protein level)

neXtProt

NX_P17600

Antibodypedia

SYN1 antibodies
 

PROTEIN VIEW

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SYN1-001
 
SYN1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SYN1-001 ENSP00000295987
ENST00000295987
P17600
Show all »
Show » Show » 705 74.1 No 0
SYN1-002 ENSP00000343206
ENST00000340666
P17600
Show all »
Show » Show » 669 70 No 0