JARID2

GENE INFORMATION

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Gene name

JARID2 (HGNC Symbol)

Synonyms

JMJ

Description

Jumonji, AT rich interactive domain 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a Jumonji- and AT-rich interaction domain (ARID)-domain-containing protein. The encoded protein is a DNA-binding protein that functions as a transcriptional repressor. This protein interacts with the Polycomb repressive complex 2 (PRC2) which plays an essential role in regulating gene expression during embryonic development. This protein facilitates the recruitment of the PRC2 complex to target genes. Alternate splicing results in multiple transcript variants. Mutations in this gene are associated with chronic myeloid malignancies. [provided by RefSeq, May 2012]

Chromosome

6

Cytoband

p22.3

Chromosome location (bp)

15246296 - 15522040

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000008083 (version 78.38)

Entrez gene

3720

UniProt

Q92833 (UniProt - Evidence at protein level)

neXtProt

NX_Q92833

Antibodypedia

JARID2 antibodies
 

PROTEIN VIEW

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JARID2-001
 
JARID2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

JARID2-001 ENSP00000341280
ENST00000341776
Q92833
Show all »
Show » Show » 1246 138.7 No 0
JARID2-201 ENSP00000380478
ENST00000397311
Q92833
Show all »
Show » Show » 1074 119.7 No 0