SEC62

GENE INFORMATION

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Gene name

SEC62 (HGNC Symbol)

Synonyms

Dtrp1, HTP1, TLOC1

Description

SEC62 homolog (S. cerevisiae) (HGNC Symbol)

Entrez gene summary

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

q26.2

Chromosome location (bp)

169966635 - 169998373

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000008952 (version 78.38)

Entrez gene

7095

UniProt

Q99442 (UniProt - Evidence at protein level)

neXtProt

NX_Q99442

Antibodypedia

SEC62 antibodies
 

PROTEIN VIEW

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SEC62-001
 
SEC62-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SEC62-001 ENSP00000337688
ENST00000337002
Q99442
Show all »
Show » Show » 399 45.9 No 2
SEC62-002 ENSP00000420331
ENST00000480708
Q99442
Show all »
Show » Show » 399 45.9 No 2