CD6

GENE INFORMATION

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Gene name

CD6 (HGNC Symbol)

Synonyms

Tp120

Description

CD6 molecule (HGNC Symbol)

Entrez gene summary

This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Chromosome

11

Cytoband

q12.2

Chromosome location (bp)

60971680 - 61020377

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000013725 (version 78.38)

Entrez gene

923

UniProt

P30203 (UniProt - Evidence at protein level)

neXtProt

NX_P30203

Antibodypedia

CD6 antibodies
 

PROTEIN VIEW

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CD6-001
 
CD6-005
 
CD6-006
 
CD6-007
 
CD6-008
 
CD6-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CD6-001 ENSP00000323280
ENST00000313421
P30203
Show all »
Show » Show » 668 71.8 Yes 1
CD6-005 ENSP00000440055
ENST00000542157
F6UFK6
Show all »
Show » Show » 278 29.2 Yes 0
CD6-006 ENSP00000410638
ENST00000433107
E7ER04
Show all »
Show » Show » 422 45 Yes 1
CD6-007 ENSP00000390676
ENST00000452451
P30203
Show all »
Show » Show » 592 63.6 Yes 1
CD6-008 ENSP00000340628
ENST00000352009
P30203
Show all »
Show » Show » 601 64.7 Yes 1
CD6-013 ENSP00000443747
ENST00000538611
Show » Show » 186 20 No 1