Splice variant |
Ensembl |
UniProt |
Protein class |
Gene ontology |
Length (aa) |
Molecular mass (kDa) |
Signal peptide (predicted) |
Transmembrane regions (predicted)
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HGF-001 |
ENSP00000222390
ENST00000222390
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P14210 Show all »
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P14210 [Direct mapping]Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain C9JDP4 [Target identity:19%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000396307} C9JS80 [Target identity:16%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000388592}
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Enzymes Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins RAS pathway related proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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|
728 |
83.1 |
Yes |
0 |
HGF-002 |
ENSP00000408270
ENST00000453411
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P14210 Show all »
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P14210 [Direct mapping]Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain C9JDP4 [Target identity:49%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000396307} C9JS80 [Target identity:41%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000388592}
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Enzymes Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins RAS pathway related proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0001837 [epithelial to mesenchymal transition] GO:0002576 [platelet degranulation] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0007067 [mitotic nuclear division] GO:0007596 [blood coagulation] GO:0008083 [growth factor activity] GO:0014068 [positive regulation of phosphatidylinositol 3-kinase signaling] GO:0016020 [membrane] GO:0030168 [platelet activation] GO:0030335 [positive regulation of cell migration] GO:0031093 [platelet alpha granule lumen] GO:0035729 [cellular response to hepatocyte growth factor stimulus] GO:0042056 [chemoattractant activity] GO:0042802 [identical protein binding] GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0045669 [positive regulation of osteoblast differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048012 [hepatocyte growth factor receptor signaling pathway] GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation] GO:0050918 [positive chemotaxis] GO:0060326 [cell chemotaxis] GO:0060665 [regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling] GO:0090201 [negative regulation of release of cytochrome c from mitochondria] GO:1901299 [negative regulation of hydrogen peroxide-mediated programmed cell death] GO:2000573 [positive regulation of DNA biosynthetic process]
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285 |
33.2 |
Yes |
0 |
HGF-003 |
ENSP00000389854
ENST00000444829
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P14210 Show all »
« Hide
P14210 [Direct mapping]Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain C9JDP4 [Target identity:48%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000396307} C9JS80 [Target identity:40%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000388592}
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« Hide
Enzymes Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins RAS pathway related proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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« Hide
GO:0001837 [epithelial to mesenchymal transition] GO:0002576 [platelet degranulation] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0007067 [mitotic nuclear division] GO:0007596 [blood coagulation] GO:0008083 [growth factor activity] GO:0014068 [positive regulation of phosphatidylinositol 3-kinase signaling] GO:0016020 [membrane] GO:0030168 [platelet activation] GO:0030335 [positive regulation of cell migration] GO:0031093 [platelet alpha granule lumen] GO:0035729 [cellular response to hepatocyte growth factor stimulus] GO:0042056 [chemoattractant activity] GO:0042802 [identical protein binding] GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0045669 [positive regulation of osteoblast differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048012 [hepatocyte growth factor receptor signaling pathway] GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation] GO:0050918 [positive chemotaxis] GO:0060326 [cell chemotaxis] GO:0060665 [regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling] GO:0090201 [negative regulation of release of cytochrome c from mitochondria] GO:1901299 [negative regulation of hydrogen peroxide-mediated programmed cell death] GO:2000573 [positive regulation of DNA biosynthetic process]
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290 |
33.8 |
Yes |
0 |
HGF-004 |
ENSP00000413829
ENST00000423064
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P14210 Show all »
« Hide
P14210 [Direct mapping]Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain Q59H59 [Target identity:100%; Query identity:85%]Hepatocyte growth factor isoform 1 preproprotein variant {ECO:0000313|EMBL:BAD92137.1} C9JDP4 [Target identity:67%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000396307} C9JS80 [Target identity:56%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000388592}
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Enzymes Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins RAS pathway related proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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Show »
« Hide
GO:0001837 [epithelial to mesenchymal transition] GO:0002576 [platelet degranulation] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0007067 [mitotic nuclear division] GO:0007596 [blood coagulation] GO:0008083 [growth factor activity] GO:0014068 [positive regulation of phosphatidylinositol 3-kinase signaling] GO:0016020 [membrane] GO:0030168 [platelet activation] GO:0030335 [positive regulation of cell migration] GO:0031093 [platelet alpha granule lumen] GO:0035729 [cellular response to hepatocyte growth factor stimulus] GO:0042056 [chemoattractant activity] GO:0042802 [identical protein binding] GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0045669 [positive regulation of osteoblast differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048012 [hepatocyte growth factor receptor signaling pathway] GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation] GO:0050918 [positive chemotaxis] GO:0060326 [cell chemotaxis] GO:0060665 [regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling] GO:0090201 [negative regulation of release of cytochrome c from mitochondria] GO:1901299 [negative regulation of hydrogen peroxide-mediated programmed cell death] GO:2000573 [positive regulation of DNA biosynthetic process]
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210 |
24.1 |
Yes |
0 |
HGF-005 |
ENSP00000391238
ENST00000457544
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P14210 Show all »
« Hide
P14210 [Direct mapping]Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain C9JDP4 [Target identity:19%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000396307} C9JS80 [Target identity:16%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000388592}
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Show »
« Hide
Enzymes Peptidases Serine-type peptidases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins RAS pathway related proteins Cancer-related genes Candidate cancer biomarkers Mutational cancer driver genes Candidate cardiovascular disease genes Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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Show »
« Hide
GO:0001837 [epithelial to mesenchymal transition] GO:0002576 [platelet degranulation] GO:0003824 [catalytic activity] GO:0004252 [serine-type endopeptidase activity] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0006508 [proteolysis] GO:0007067 [mitotic nuclear division] GO:0007596 [blood coagulation] GO:0008083 [growth factor activity] GO:0014068 [positive regulation of phosphatidylinositol 3-kinase signaling] GO:0016020 [membrane] GO:0030168 [platelet activation] GO:0030335 [positive regulation of cell migration] GO:0031093 [platelet alpha granule lumen] GO:0035729 [cellular response to hepatocyte growth factor stimulus] GO:0042056 [chemoattractant activity] GO:0042802 [identical protein binding] GO:0043154 [negative regulation of cysteine-type endopeptidase activity involved in apoptotic process] GO:0045669 [positive regulation of osteoblast differentiation] GO:0045944 [positive regulation of transcription from RNA polymerase II promoter] GO:0048012 [hepatocyte growth factor receptor signaling pathway] GO:0050731 [positive regulation of peptidyl-tyrosine phosphorylation] GO:0050918 [positive chemotaxis] GO:0060326 [cell chemotaxis] GO:0060665 [regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling] GO:0090201 [negative regulation of release of cytochrome c from mitochondria] GO:1901299 [negative regulation of hydrogen peroxide-mediated programmed cell death] GO:2000573 [positive regulation of DNA biosynthetic process]
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723 |
82.6 |
Yes |
0 |
HGF-006 |
ENSP00000395468
ENST00000453018
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C9JJ35 Show all »
« Hide
C9JJ35 [Target identity:100%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000395468}
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Predicted intracellular proteins RAS pathway related proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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58 |
6.7 |
No |
0 |
HGF-007 |
ENSP00000388592
ENST00000421558
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C9JS80 Show all »
« Hide
C9JS80 [Target identity:100%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000388592}
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Show »
« Hide
MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins RAS pathway related proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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|
118 |
13.6 |
Yes |
0 |
HGF-008 |
ENSP00000396307
ENST00000412881
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C9JDP4 Show all »
« Hide
C9JDP4 [Target identity:100%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000396307} C9JS80 [Target identity:83%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000388592}
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Show »
« Hide
MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins RAS pathway related proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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|
141 |
16.2 |
Yes |
0 |
HGF-201 |
ENSP00000346164
ENST00000354224
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C9WSJ3 Show all »
« Hide
C9WSJ3 [Target identity:100%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000346164}; Hepatocyte growth factor isoform 6 {ECO:0000313|EMBL:ACX45437.1} C9JDP4 [Target identity:76%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000396307} C9JS80 [Target identity:64%; Query identity:100%]Hepatocyte growth factor beta chain {ECO:0000313|Ensembl:ENSP00000388592}
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Show »
« Hide
MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins RAS pathway related proteins Cancer-related genes Mutational cancer driver genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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184 |
21 |
Yes |
0 |