UBR2

GENE INFORMATION

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Gene name

UBR2 (HGNC Symbol)

Synonyms

bA49A4.1, C6orf133, dJ392M17.3, KIAA0349

Description

Ubiquitin protein ligase E3 component n-recognin 2 (HGNC Symbol)

Entrez gene summary

This gene encodes an E3 ubiquitin ligase of the N-end rule proteolytic pathway that targets proteins with destabilizing N-terminal residues for polyubiquitylation and proteasome-mediated degradation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]

Chromosome

6

Cytoband

p21.1

Chromosome location (bp)

42564062 - 42693504

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000024048 (version 78.38)

Entrez gene

23304

UniProt

Q8IWV8 (UniProt - Evidence at protein level)

neXtProt

NX_Q8IWV8

Antibodypedia

UBR2 antibodies
 

PROTEIN VIEW

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UBR2-001
 
UBR2-002
 
UBR2-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

UBR2-001 ENSP00000361990
ENST00000372899
Q8IWV8
Show all »
Show » Show » 1755 200.5 No 2
UBR2-002 ENSP00000361992
ENST00000372901
Q8IWV8
Show all »
Show » Show » 1755 200.5 No 2
UBR2-003 ENSP00000361994
ENST00000372903
Q8IWV8
Show all »
Show » Show » 439 50 No 0