VRK2

GENE INFORMATION

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Gene name

VRK2

Synonyms

Description

Vaccinia related kinase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014]

Chromosome

2

Cytoband

p16.1

Chromosome location (bp)

57907651 - 58159920

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000028116 (version 78.38)

Entrez gene

7444

UniProt

Q86Y07 (UniProt - Evidence at protein level)

neXtProt

NX_Q86Y07

Antibodypedia

VRK2 antibodies
 

PROTEIN VIEW

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VRK2-001
 
VRK2-003
 
VRK2-004
 
VRK2-005
 
VRK2-008
 
VRK2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VRK2-001 ENSP00000342381
ENST00000340157
Q86Y07
Show all »
Show » Show » 508 58.1 No 1
VRK2-003 ENSP00000404961
ENST00000428021
E7ERS5
Show all »
Show » Show » 82 9.5 No 0
VRK2-004 ENSP00000402375
ENST00000417641
Q86Y07
Show all »
Show » Show » 396 45 No 0
VRK2-005 ENSP00000408002
ENST00000435505
Q86Y07
Show all »
Show » Show » 508 58.1 No 1
VRK2-008 ENSP00000398323
ENST00000440705
Q86Y07
Show all »
Show » Show » 485 55.4 No 1
VRK2-201 ENSP00000404156
ENST00000412104
Q86Y07
Show all »
Show » Show » 390 44.4 No 1