ARID4A

GENE INFORMATION

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Gene name

ARID4A (HGNC Symbol)

Synonyms

RBBP1, RBP-1, RBP1

Description

AT rich interactive domain 4A (RBP1-like) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q23.1

Chromosome location (bp)

58298385 - 58373887

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000032219 (version 78.38)

Entrez gene

5926

UniProt

P29374 (UniProt - Evidence at protein level)

neXtProt

NX_P29374

Antibodypedia

ARID4A antibodies
 

PROTEIN VIEW

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ARID4A-001
 
ARID4A-002
 
ARID4A-003
 
ARID4A-005
 
ARID4A-006
 
ARID4A-009
 
ARID4A-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARID4A-001 ENSP00000347602
ENST00000355431
P29374
Show all »
Show » Show » 1257 142.8 No 0
ARID4A-002 ENSP00000397368
ENST00000431317
P29374
Show all »
Show » Show » 1188 135 No 0
ARID4A-003 ENSP00000378597
ENST00000395168
P29374
Show all »
Show » Show » 1203 136.5 No 0
ARID4A-005 ENSP00000392567
ENST00000445108
C9J1W3
Show all »
Show » 265 30 No 0
ARID4A-006 ENSP00000415872
ENST00000424658
C9JIF4
Show all »
Show » 54 6 No 0
ARID4A-009 ENSP00000416053
ENST00000417477
H7C485
Show all »
Show » Show » 748 85.3 No 0
ARID4A-201 ENSP00000344556
ENST00000348476
P29374
Show all »
Show » Show » 1188 135 No 0