PARP3

GENE INFORMATION

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Gene name

PARP3 (HGNC Symbol)

Synonyms

ADPRT3, ADPRTL3, hPARP-3, IRT1, pADPRT-3

Description

Poly (ADP-ribose) polymerase family, member 3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

p21.2

Chromosome location (bp)

51942345 - 51948867

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000041880 (version 78.38)

Entrez gene

10039

UniProt

Q9Y6F1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6F1

Antibodypedia

PARP3 antibodies
 

PROTEIN VIEW

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PARP3-001
 
PARP3-002
 
PARP3-005
 
PARP3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PARP3-001 ENSP00000381740
ENST00000398755
Q9Y6F1
Show all »
Show » Show » 540 60.9 No 0
PARP3-002 ENSP00000395951
ENST00000417220
A0A024R2X5
Show all »
Show » Show » 533 60.1 No 0
PARP3-005 ENSP00000417625
ENST00000498510
Show » Show » 332 37.8 No 0
PARP3-201 ENSP00000401511
ENST00000431474
A0A024R2X5
Show all »
Show » Show » 533 60.1 No 0