HDAC9 - Gene info - The Human Protein Atlas

HDAC9

TISSUE

SUBCELL

CELL LINE

CANCER

GENE INFORMATION

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Gene name	HDAC9 (HGNC Symbol)
Synonyms	HD7, HDAC, HDAC7B, KIAA0744, MITR
Description	Histone deacetylase 9 (HGNC Symbol)
Entrez gene summary	Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	p21.1
Chromosome location (bp)	18086949 - 19002416
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000048052 (version 78.38)
Entrez gene	9734
UniProt	Q9UKV0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UKV0
Antibodypedia	HDAC9 antibodies

PROTEIN VIEW

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HDAC9-001		HDAC9-002		HDAC9-004		HDAC9-005		HDAC9-006		HDAC9-008		HDAC9-010		HDAC9-011		HDAC9-013		HDAC9-015		HDAC9-017		HDAC9-021		HDAC9-022		HDAC9-023		HDAC9-025		HDAC9-201

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)	Transmembrane regions (predicted)
HDAC9-001	ENSP00000384657 ENST00000406451	Q9UKV0 Show all » « Hide Q9UKV0 [Direct mapping] Histone deacetylase 9 Q75N15 [Target identity:37%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07424.1} Q75N14 [Target identity:36%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07423.1} Q8N926 [Target identity:29%; Query identity:100%] cDNA FLJ38501 fis, clone HCHON1000176, moderately similar to Histone deacetylase 5 {ECO:0000313\|EMBL:BAC04630.1} Q75N08 [Target identity:16%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07409.1} Q75N10 [Target identity:14%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07401.1} C9JD56 [Target identity:10%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000404763} C9JLX1 [Target identity:2%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000409003}	Show » « Hide Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Disease related genes FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014)	Show » « Hide GO:0000118 [histone deacetylase complex] GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003714 [transcription corepressor activity] GO:0004407 [histone deacetylase activity] GO:0005080 [protein kinase C binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006954 [inflammatory response] GO:0007219 [Notch signaling pathway] GO:0007507 [heart development] GO:0008134 [transcription factor binding] GO:0016568 [chromatin modification] GO:0016575 [histone deacetylation] GO:0030183 [B cell differentiation] GO:0032041 [NAD-dependent histone deacetylase activity (H3-K14 specific)] GO:0032869 [cellular response to insulin stimulus] GO:0033558 [protein deacetylase activity] GO:0034983 [peptidyl-lysine deacetylation] GO:0035097 [histone methyltransferase complex] GO:0042113 [B cell activation] GO:0042826 [histone deacetylase binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0046969 [NAD-dependent histone deacetylase activity (H3-K9 specific)] GO:0046970 [NAD-dependent histone deacetylase activity (H4-K16 specific)] GO:0048742 [regulation of skeletal muscle fiber development] GO:0051153 [regulation of striated muscle cell differentiation] GO:0070491 [repressing transcription factor binding] GO:0070932 [histone H3 deacetylation] GO:0070933 [histone H4 deacetylation] GO:0090050 [positive regulation of cell migration involved in sprouting angiogenesis] GO:0097372 [NAD-dependent histone deacetylase activity (H3-K18 specific)]	1066	117.2	No	0
HDAC9-002	ENSP00000384382 ENST00000405010	Q9UKV0 Show all » « Hide Q9UKV0 [Direct mapping] Histone deacetylase 9 Q75N16 [Target identity:69%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07422.1} Q75N15 [Target identity:67%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07424.1} Q75N14 [Target identity:66%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07423.1} Q75N08 [Target identity:30%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07409.1} C9JD56 [Target identity:18%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000404763} C9JLX1 [Target identity:3%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000409003}	Show » « Hide Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Disease related genes FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014)	Show » « Hide GO:0000118 [histone deacetylase complex] GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003714 [transcription corepressor activity] GO:0004407 [histone deacetylase activity] GO:0005080 [protein kinase C binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006954 [inflammatory response] GO:0007219 [Notch signaling pathway] GO:0007507 [heart development] GO:0008134 [transcription factor binding] GO:0016575 [histone deacetylation] GO:0030183 [B cell differentiation] GO:0032041 [NAD-dependent histone deacetylase activity (H3-K14 specific)] GO:0032869 [cellular response to insulin stimulus] GO:0033558 [protein deacetylase activity] GO:0034983 [peptidyl-lysine deacetylation] GO:0035097 [histone methyltransferase complex] GO:0042113 [B cell activation] GO:0042826 [histone deacetylase binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0046969 [NAD-dependent histone deacetylase activity (H3-K9 specific)] GO:0046970 [NAD-dependent histone deacetylase activity (H4-K16 specific)] GO:0048742 [regulation of skeletal muscle fiber development] GO:0051153 [regulation of striated muscle cell differentiation] GO:0070491 [repressing transcription factor binding] GO:0070932 [histone H3 deacetylation] GO:0070933 [histone H4 deacetylation] GO:0090050 [positive regulation of cell migration involved in sprouting angiogenesis] GO:0097372 [NAD-dependent histone deacetylase activity (H3-K18 specific)]	590	65.9	No	0
HDAC9-004	ENSP00000384017 ENST00000406072	B5MCF1 Show all » « Hide B5MCF1 [Target identity:100%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000384017} B7Z3P7 [Target identity:95%; Query identity:100%] cDNA FLJ53343, highly similar to Histone deacetylase 9 {ECO:0000313\|EMBL:BAH12283.1}; cDNA, FLJ79008, highly similar to Histone deacetylase 9 {ECO:0000313\|EMBL:BAH14480.1} C9J1W4 [Target identity:25%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000392564} C9IZS0 [Target identity:23%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000412497} C9J835 [Target identity:12%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000411422} C9JLX1 [Target identity:3%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000409003}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014)		577	64.2	No	0
HDAC9-005	ENSP00000401669 ENST00000417496	Q9UKV0 Show all » « Hide Q9UKV0 [Direct mapping] Histone deacetylase 9 Q75N08 [Target identity:30%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07409.1} C9JD56 [Target identity:18%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000404763} C9JLX1 [Target identity:3%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000409003}	Show » « Hide Enzymes ENZYME proteins Hydrolases THUMBUP predicted membrane proteins Phobius predicted secreted proteins Predicted intracellular proteins Plasma proteins Disease related genes FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014)	Show » « Hide GO:0000118 [histone deacetylase complex] GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003714 [transcription corepressor activity] GO:0004407 [histone deacetylase activity] GO:0005080 [protein kinase C binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006954 [inflammatory response] GO:0007219 [Notch signaling pathway] GO:0007507 [heart development] GO:0008134 [transcription factor binding] GO:0016575 [histone deacetylation] GO:0030183 [B cell differentiation] GO:0032041 [NAD-dependent histone deacetylase activity (H3-K14 specific)] GO:0032869 [cellular response to insulin stimulus] GO:0033558 [protein deacetylase activity] GO:0034983 [peptidyl-lysine deacetylation] GO:0035097 [histone methyltransferase complex] GO:0042113 [B cell activation] GO:0042826 [histone deacetylase binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0046969 [NAD-dependent histone deacetylase activity (H3-K9 specific)] GO:0046970 [NAD-dependent histone deacetylase activity (H4-K16 specific)] GO:0048742 [regulation of skeletal muscle fiber development] GO:0051153 [regulation of striated muscle cell differentiation] GO:0070491 [repressing transcription factor binding] GO:0070932 [histone H3 deacetylation] GO:0070933 [histone H4 deacetylation] GO:0090050 [positive regulation of cell migration involved in sprouting angiogenesis] GO:0097372 [NAD-dependent histone deacetylase activity (H3-K18 specific)]	588	65.5	No	0
HDAC9-006	ENSP00000409003 ENST00000433709	C9JLX1 Show all » « Hide C9JLX1 [Target identity:95%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000409003}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014)		23	2.4	No	0
HDAC9-008	ENSP00000412497 ENST00000413509	C9IZS0 Show all » « Hide C9IZS0 [Target identity:100%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000412497} C9J835 [Target identity:50%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000411422} C9JLX1 [Target identity:15%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000409003}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014)		138	16.5	No	0
HDAC9-010	ENSP00000411422 ENST00000430454	C9J835 Show all » « Hide C9J835 [Target identity:98%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000411422}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014)		71	8.6	No	0
HDAC9-011	ENSP00000392564 ENST00000413380	C9J1W4 Show all » « Hide C9J1W4 [Target identity:100%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000392564} C9IZS0 [Target identity:93%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000412497} C9J835 [Target identity:47%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000411422} C9JLX1 [Target identity:14%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000409003}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014)		148	17.6	No	0
HDAC9-013	ENSP00000404763 ENST00000441986	C9JD56 Show all » « Hide C9JD56 [Target identity:100%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000404763}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014)		110	13.3	No	0
HDAC9-015	ENSP00000388568 ENST00000456174	Q9UKV0 Show all » « Hide Q9UKV0 [Direct mapping] Histone deacetylase 9 Q75N16 [Target identity:73%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07422.1} Q75N15 [Target identity:70%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07424.1} Q75N14 [Target identity:69%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07423.1} C9J835 [Target identity:12%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000411422}	Show » « Hide Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Disease related genes FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014)	Show » « Hide GO:0000118 [histone deacetylase complex] GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003714 [transcription corepressor activity] GO:0004407 [histone deacetylase activity] GO:0005080 [protein kinase C binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006954 [inflammatory response] GO:0007219 [Notch signaling pathway] GO:0007507 [heart development] GO:0008134 [transcription factor binding] GO:0016575 [histone deacetylation] GO:0030183 [B cell differentiation] GO:0032041 [NAD-dependent histone deacetylase activity (H3-K14 specific)] GO:0032869 [cellular response to insulin stimulus] GO:0033558 [protein deacetylase activity] GO:0034983 [peptidyl-lysine deacetylation] GO:0035097 [histone methyltransferase complex] GO:0042113 [B cell activation] GO:0042826 [histone deacetylase binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0046969 [NAD-dependent histone deacetylase activity (H3-K9 specific)] GO:0046970 [NAD-dependent histone deacetylase activity (H4-K16 specific)] GO:0048742 [regulation of skeletal muscle fiber development] GO:0051153 [regulation of striated muscle cell differentiation] GO:0070491 [repressing transcription factor binding] GO:0070932 [histone H3 deacetylation] GO:0070933 [histone H4 deacetylation] GO:0090050 [positive regulation of cell migration involved in sprouting angiogenesis] GO:0097372 [NAD-dependent histone deacetylase activity (H3-K18 specific)]	562	62.9	No	0
HDAC9-017	ENSP00000383912 ENST00000401921	Q9UKV0 Show all » « Hide Q9UKV0 [Direct mapping] Histone deacetylase 9 Q8N926 [Target identity:30%; Query identity:100%] cDNA FLJ38501 fis, clone HCHON1000176, moderately similar to Histone deacetylase 5 {ECO:0000313\|EMBL:BAC04630.1} Q75N10 [Target identity:15%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07401.1} C9J1W4 [Target identity:14%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000392564} C9IZS0 [Target identity:13%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000412497} C9J835 [Target identity:6%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000411422} C9JLX1 [Target identity:2%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000409003}	Show » « Hide Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Disease related genes FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014)	Show » « Hide GO:0000118 [histone deacetylase complex] GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003714 [transcription corepressor activity] GO:0004407 [histone deacetylase activity] GO:0005080 [protein kinase C binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006954 [inflammatory response] GO:0007219 [Notch signaling pathway] GO:0007507 [heart development] GO:0008134 [transcription factor binding] GO:0016568 [chromatin modification] GO:0016575 [histone deacetylation] GO:0030183 [B cell differentiation] GO:0032041 [NAD-dependent histone deacetylase activity (H3-K14 specific)] GO:0032869 [cellular response to insulin stimulus] GO:0033558 [protein deacetylase activity] GO:0034983 [peptidyl-lysine deacetylation] GO:0035097 [histone methyltransferase complex] GO:0042113 [B cell activation] GO:0042826 [histone deacetylase binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0046969 [NAD-dependent histone deacetylase activity (H3-K9 specific)] GO:0046970 [NAD-dependent histone deacetylase activity (H4-K16 specific)] GO:0048742 [regulation of skeletal muscle fiber development] GO:0051153 [regulation of striated muscle cell differentiation] GO:0070491 [repressing transcription factor binding] GO:0070932 [histone H3 deacetylation] GO:0070933 [histone H4 deacetylation] GO:0090050 [positive regulation of cell migration involved in sprouting angiogenesis] GO:0097372 [NAD-dependent histone deacetylase activity (H3-K18 specific)]	1025	112.5	No	0
HDAC9-021	ENSP00000408617 ENST00000441542	Q9UKV0 Show all » « Hide Q9UKV0 [Direct mapping] Histone deacetylase 9 Q75N15 [Target identity:37%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07424.1} Q75N14 [Target identity:36%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07423.1} Q8N926 [Target identity:29%; Query identity:100%] cDNA FLJ38501 fis, clone HCHON1000176, moderately similar to Histone deacetylase 5 {ECO:0000313\|EMBL:BAC04630.1} Q75N10 [Target identity:14%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07401.1} C9J1W4 [Target identity:13%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000392564} C9IZS0 [Target identity:12%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000412497} C9J835 [Target identity:6%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000411422} C9JLX1 [Target identity:2%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000409003}	Show » « Hide Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Disease related genes FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014)	Show » « Hide GO:0000118 [histone deacetylase complex] GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003714 [transcription corepressor activity] GO:0004407 [histone deacetylase activity] GO:0005080 [protein kinase C binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006954 [inflammatory response] GO:0007219 [Notch signaling pathway] GO:0007507 [heart development] GO:0008134 [transcription factor binding] GO:0016568 [chromatin modification] GO:0016575 [histone deacetylation] GO:0030183 [B cell differentiation] GO:0032041 [NAD-dependent histone deacetylase activity (H3-K14 specific)] GO:0032869 [cellular response to insulin stimulus] GO:0033558 [protein deacetylase activity] GO:0034983 [peptidyl-lysine deacetylation] GO:0035097 [histone methyltransferase complex] GO:0042113 [B cell activation] GO:0042826 [histone deacetylase binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0046969 [NAD-dependent histone deacetylase activity (H3-K9 specific)] GO:0046970 [NAD-dependent histone deacetylase activity (H4-K16 specific)] GO:0048742 [regulation of skeletal muscle fiber development] GO:0051153 [regulation of striated muscle cell differentiation] GO:0070491 [repressing transcription factor binding] GO:0070932 [histone H3 deacetylation] GO:0070933 [histone H4 deacetylation] GO:0090050 [positive regulation of cell migration involved in sprouting angiogenesis] GO:0097372 [NAD-dependent histone deacetylase activity (H3-K18 specific)]	1069	117.6	No	0
HDAC9-022	ENSP00000430036 ENST00000524023	Q9UKV0 Show all » « Hide Q9UKV0 [Direct mapping] Histone deacetylase 9 C9JD56 [Target identity:21%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000404763}	Show » « Hide Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Disease related genes FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014)	Show » « Hide GO:0000118 [histone deacetylase complex] GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003714 [transcription corepressor activity] GO:0004407 [histone deacetylase activity] GO:0005080 [protein kinase C binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006954 [inflammatory response] GO:0007219 [Notch signaling pathway] GO:0007507 [heart development] GO:0008134 [transcription factor binding] GO:0016575 [histone deacetylation] GO:0030183 [B cell differentiation] GO:0032041 [NAD-dependent histone deacetylase activity (H3-K14 specific)] GO:0032869 [cellular response to insulin stimulus] GO:0033558 [protein deacetylase activity] GO:0034983 [peptidyl-lysine deacetylation] GO:0035097 [histone methyltransferase complex] GO:0042113 [B cell activation] GO:0042826 [histone deacetylase binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0046969 [NAD-dependent histone deacetylase activity (H3-K9 specific)] GO:0046970 [NAD-dependent histone deacetylase activity (H4-K16 specific)] GO:0048742 [regulation of skeletal muscle fiber development] GO:0051153 [regulation of striated muscle cell differentiation] GO:0070491 [repressing transcription factor binding] GO:0070932 [histone H3 deacetylation] GO:0070933 [histone H4 deacetylation] GO:0090050 [positive regulation of cell migration involved in sprouting angiogenesis] GO:0097372 [NAD-dependent histone deacetylase activity (H3-K18 specific)]	513	57.1	No	0
HDAC9-023	ENSP00000410337 ENST00000432645	Q9UKV0 Show all » « Hide Q9UKV0 [Direct mapping] Histone deacetylase 9 Q75N15 [Target identity:39%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07424.1} Q75N14 [Target identity:38%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07423.1} Q75N08 [Target identity:17%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07409.1} Q75N10 [Target identity:15%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07401.1} C9JD56 [Target identity:10%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000404763} C9JLX1 [Target identity:2%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000409003}	Show » « Hide Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Disease related genes FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014)	Show » « Hide GO:0000118 [histone deacetylase complex] GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003714 [transcription corepressor activity] GO:0004407 [histone deacetylase activity] GO:0005080 [protein kinase C binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006954 [inflammatory response] GO:0007219 [Notch signaling pathway] GO:0007507 [heart development] GO:0008134 [transcription factor binding] GO:0016568 [chromatin modification] GO:0016575 [histone deacetylation] GO:0030183 [B cell differentiation] GO:0032041 [NAD-dependent histone deacetylase activity (H3-K14 specific)] GO:0032869 [cellular response to insulin stimulus] GO:0033558 [protein deacetylase activity] GO:0034983 [peptidyl-lysine deacetylation] GO:0035097 [histone methyltransferase complex] GO:0042113 [B cell activation] GO:0042826 [histone deacetylase binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0046969 [NAD-dependent histone deacetylase activity (H3-K9 specific)] GO:0046970 [NAD-dependent histone deacetylase activity (H4-K16 specific)] GO:0048742 [regulation of skeletal muscle fiber development] GO:0051153 [regulation of striated muscle cell differentiation] GO:0070491 [repressing transcription factor binding] GO:0070932 [histone H3 deacetylation] GO:0070933 [histone H4 deacetylation] GO:0090050 [positive regulation of cell migration involved in sprouting angiogenesis] GO:0097372 [NAD-dependent histone deacetylase activity (H3-K18 specific)]	1011	111.3	No	0
HDAC9-025	ENSP00000395655 ENST00000428307	Q9UKV0 Show all » « Hide Q9UKV0 [Direct mapping] Histone deacetylase 9 Q75N08 [Target identity:32%; Query identity:100%] Putative uncharacterized protein HDAC9 {ECO:0000313\|EMBL:AAS07409.1} C9JD56 [Target identity:20%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000404763} C9JLX1 [Target identity:4%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000409003}	Show » « Hide Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Plasma proteins Disease related genes FDA approved drug targets Small molecule drugs Protein evidence (Kim et al 2014)	Show » « Hide GO:0000118 [histone deacetylase complex] GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003714 [transcription corepressor activity] GO:0004407 [histone deacetylase activity] GO:0005080 [protein kinase C binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005667 [transcription factor complex] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006954 [inflammatory response] GO:0007219 [Notch signaling pathway] GO:0007507 [heart development] GO:0008134 [transcription factor binding] GO:0016575 [histone deacetylation] GO:0030183 [B cell differentiation] GO:0032041 [NAD-dependent histone deacetylase activity (H3-K14 specific)] GO:0032869 [cellular response to insulin stimulus] GO:0033558 [protein deacetylase activity] GO:0034983 [peptidyl-lysine deacetylation] GO:0035097 [histone methyltransferase complex] GO:0042113 [B cell activation] GO:0042826 [histone deacetylase binding] GO:0045892 [negative regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0046969 [NAD-dependent histone deacetylase activity (H3-K9 specific)] GO:0046970 [NAD-dependent histone deacetylase activity (H4-K16 specific)] GO:0048742 [regulation of skeletal muscle fiber development] GO:0051153 [regulation of striated muscle cell differentiation] GO:0070491 [repressing transcription factor binding] GO:0070932 [histone H3 deacetylation] GO:0070933 [histone H4 deacetylation] GO:0090050 [positive regulation of cell migration involved in sprouting angiogenesis] GO:0097372 [NAD-dependent histone deacetylase activity (H3-K18 specific)]	546	60.8	No	0
HDAC9-201	ENSP00000478829 ENST00000622668	B7Z3P7 Show all » « Hide B7Z3P7 [Target identity:100%; Query identity:100%] cDNA FLJ53343, highly similar to Histone deacetylase 9 {ECO:0000313\|EMBL:BAH12283.1}; cDNA, FLJ79008, highly similar to Histone deacetylase 9 {ECO:0000313\|EMBL:BAH14480.1} C9J1W4 [Target identity:26%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000392564} C9IZS0 [Target identity:25%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000412497} C9J835 [Target identity:12%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000411422} C9JLX1 [Target identity:4%; Query identity:100%] Histone deacetylase 9 {ECO:0000313\|Ensembl:ENSP00000409003}	Show » « Hide Predicted intracellular proteins Protein evidence (Kim et al 2014)		549	61.1	No	0

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.