KMT2C

GENE INFORMATION

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Gene name

KMT2C (HGNC Symbol)

Synonyms

HALR, KIAA1506, MLL3

Description

Lysine (K)-specific methyltransferase 2C (HGNC Symbol)

Entrez gene summary

This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

q36.1

Chromosome location (bp)

152134922 - 152436005

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000055609 (version 78.38)

Entrez gene

58508

UniProt

Q8NEZ4 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NEZ4

Antibodypedia

KMT2C antibodies
 

PROTEIN VIEW

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KMT2C-001
 
KMT2C-008
 
KMT2C-009
 
KMT2C-010
 
KMT2C-013
 
KMT2C-015
 
KMT2C-017
 
KMT2C-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KMT2C-001 ENSP00000262189
ENST00000262189
Q8NEZ4
Show all »
Show » Show » 4911 541.4 No 0
KMT2C-008 ENSP00000403483
ENST00000418673
Show » Show » 228 24.4 No 0
KMT2C-009 ENSP00000353218
ENST00000360104
Show » Show » 2441 269.5 No 0
KMT2C-010 ENSP00000410411
ENST00000424877
H0Y765
Show all »
Show » Show » 1524 168.5 No 0
KMT2C-013 ENSP00000410239
ENST00000452749
C9J4Z5
Show all »
Show » Show » 155 16.8 No 0
KMT2C-015 ENSP00000408001
ENST00000418061
H7C2V8
Show all »
Show » 236 25 No 0
KMT2C-017 ENSP00000454058
ENST00000558665
H0YNL4
Show all »
Show » 179 19.8 No 0
KMT2C-201 ENSP00000347325
ENST00000355193
Q8NEZ4
Show all »
Show » Show » 4911 541.4 No 0