GDI2

GENE INFORMATION

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Gene name

GDI2 (HGNC Symbol)

Synonyms

RABGDIB

Description

GDP dissociation inhibitor 2 (HGNC Symbol)

Entrez gene summary

GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

p15.1

Chromosome location (bp)

5765223 - 5842132

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000057608 (version 78.38)

Entrez gene

2665

UniProt

P50395 (UniProt - Evidence at protein level)

neXtProt

NX_P50395

Antibodypedia

GDI2 antibodies
 

PROTEIN VIEW

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GDI2-001
 
GDI2-002
 
GDI2-003
 
GDI2-004
 
GDI2-005
 
GDI2-007
 
GDI2-008
 
GDI2-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GDI2-001 ENSP00000369538
ENST00000380191
P50395
Show all »
Show » Show » 445 50.7 No 0
GDI2-002 ENSP00000369528
ENST00000380181
P50395
Show all »
Show » Show » 400 45.6 No 0
GDI2-003 ENSP00000387565
ENST00000447751
Q5SX91
Show all »
Show » Show » 203 23.1 No 0
GDI2-004 ENSP00000394177
ENST00000418688
Q5SX86
Show all »
Show » Show » 155 17.8 No 0
GDI2-005 ENSP00000401733
ENST00000456041
Q5SX87
Show all »
Show » Show » 263 29.9 No 0
GDI2-007 ENSP00000369470
ENST00000380127
Q5SX90
Show all »
Show » Show » 148 16.8 No 0
GDI2-008 ENSP00000476707
ENST00000608581
V9GYF8
Show all »
Show » Show » 130 14.9 No 0
GDI2-009 ENSP00000476832
ENST00000609712
V9GYJ7
Show all »
Show » Show » 126 14.2 No 0