CTDP1

GENE INFORMATION

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Gene name

CTDP1 (HGNC Symbol)

Synonyms

FCP1

Description

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]

Chromosome

18

Cytoband

q23

Chromosome location (bp)

79679801 - 79756623

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000060069 (version 78.38)

Entrez gene

9150

UniProt

Q9Y5B0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5B0

Antibodypedia

CTDP1 antibodies
 

PROTEIN VIEW

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CTDP1-001
 
CTDP1-002
 
CTDP1-003
 
CTDP1-005
 
CTDP1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CTDP1-001 ENSP00000484525
ENST00000613122
Q9Y5B0
Show all »
Show » Show » 961 104.4 No 0
CTDP1-002 ENSP00000075430
ENST00000075430
Q9Y5B0
Show all »
Show » Show » 867 93.5 No 0
CTDP1-003 ENSP00000465119
ENST00000591598
K7EJD2
Show all »
Show » Show » 799 87.6 No 0
CTDP1-005 ENSP00000467563
ENST00000590635
K7EPW4
Show all »
Show » Show » 78 8.7 No 0
CTDP1-201 ENSP00000299543
ENST00000299543
K7EPW4
Show all »
Show » Show » 842 92.4 No 0