CDH3

GENE INFORMATION

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Gene name

CDH3 (HGNC Symbol)

Synonyms

CDHP, PCAD

Description

Cadherin 3, type 1, P-cadherin (placental) (HGNC Symbol)

Entrez gene summary

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

q22.1

Chromosome location (bp)

68636189 - 68722616

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000062038 (version 78.38)

Entrez gene

1001

UniProt

P22223 (UniProt - Evidence at protein level)

neXtProt

NX_P22223

Antibodypedia

CDH3 antibodies
 

PROTEIN VIEW

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CDH3-001
 
CDH3-002
 
CDH3-005
 
CDH3-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDH3-001 ENSP00000264012
ENST00000264012
P22223
Show all »
Show » Show » 829 91.4 Yes 1
CDH3-002 ENSP00000398485
ENST00000429102
P22223
Show all »
Show » Show » 784 86.6 Yes 1
CDH3-005 ENSP00000463364
ENST00000568292
Show » Show » 155 17.3 No 1
CDH3-010 ENSP00000463415
ENST00000569080
J3QL75
Show all »
Show » 81 9.1 No 0