DLX3

GENE INFORMATION

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Gene name

DLX3

Synonyms

Description

Distal-less homeobox 3 (HGNC Symbol)

Entrez gene summary

Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q21.33

Chromosome location (bp)

49990005 - 49995224

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000064195 (version 78.38)

Entrez gene

1747

UniProt

O60479 (UniProt - Evidence at transcript level)

neXtProt

NX_O60479

Antibodypedia

DLX3 antibodies
 

PROTEIN VIEW

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DLX3-001
 
DLX3-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DLX3-001 ENSP00000389870
ENST00000434704
O60479
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Show » Show » 287 31.7 No 0
DLX3-002 ENSP00000449976
ENST00000512495
F8VXG1
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Show » Show » 167 18.6 No 0