OAT

GENE INFORMATION

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Gene name

OAT (HGNC Symbol)

Synonyms

HOGA

Description

Ornithine aminotransferase (HGNC Symbol)

Entrez gene summary

This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome. [provided by RefSeq, Jan 2010]

Chromosome

10

Cytoband

q26.13

Chromosome location (bp)

124397303 - 124418976

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000065154 (version 78.38)

Entrez gene

4942

UniProt

P04181 (UniProt - Evidence at protein level)

neXtProt

NX_P04181

Antibodypedia

OAT antibodies
 

PROTEIN VIEW

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OAT-001
 
OAT-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

OAT-001 ENSP00000357838
ENST00000368845
P04181
Show all »
Show » Show » 439 48.5 No 0
OAT-201 ENSP00000439042
ENST00000539214
P04181
Show all »
Show » Show » 301 32.9 No 0