ELAVL1

GENE INFORMATION

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Gene name

ELAVL1 (HGNC Symbol)

Synonyms

Hua, HUR, MelG

Description

ELAV like RNA binding protein 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. [provided by RefSeq, Sep 2012]

Chromosome

19

Cytoband

p13.2

Chromosome location (bp)

7958579 - 8445041

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000066044 (version 78.38)

Entrez gene

1994

UniProt

Q15717 (UniProt - Evidence at protein level)

neXtProt

NX_Q15717

Antibodypedia

ELAVL1 antibodies
 

PROTEIN VIEW

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ELAVL1-001
 
ELAVL1-002
 
ELAVL1-004
 
ELAVL1-005
 
ELAVL1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ELAVL1-001 ENSP00000385269
ENST00000407627
Q15717
Show all »
Show » Show » 326 36.1 No 0
ELAVL1-002 ENSP00000472197
ENST00000596459
Q15717
Show all »
Show » Show » 326 36.1 No 0
ELAVL1-004 ENSP00000471011
ENST00000596154
M0R055
Show all »
Show » Show » 133 14.9 No 0
ELAVL1-005 ENSP00000470727
ENST00000593807
M0QZR9
Show all »
Show » Show » 153 17.1 No 0
ELAVL1-201 ENSP00000264073
ENST00000351593
Q15717
Show all »
Show » Show » 326 36.1 No 0