SCT

GENE INFORMATION

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Gene name

SCT

Synonyms

Description

Secretin (HGNC Symbol)

Entrez gene summary

Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach, small intestine, and pancreas. Secretin deficiency has been implicated in autistic syndrome, suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion. [provided by RefSeq, Jul 2008]

Chromosome

11

Cytoband

p15.5

Chromosome location (bp)

626431 - 627143

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000070031 (version 78.38)

Entrez gene

6343

UniProt

P09683 (UniProt - Evidence at protein level)

neXtProt

NX_P09683

Antibodypedia

SCT antibodies
 

PROTEIN VIEW

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SCT-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SCT-001 ENSP00000176195
ENST00000176195
P09683
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