FGF10

GENE INFORMATION

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Gene name

FGF10

Synonyms

Description

Fibroblast growth factor 10 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. [provided by RefSeq, Jul 2008]

Chromosome

5

Cytoband

p12

Chromosome location (bp)

44303544 - 44389706

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000070193 (version 78.38)

Entrez gene

2255

UniProt

O15520 (UniProt - Evidence at protein level)

neXtProt

NX_O15520

Antibodypedia

FGF10 antibodies
 

PROTEIN VIEW

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FGF10-001
 
FGF10-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FGF10-001 ENSP00000264664
ENST00000264664
O15520
Show all »
Show » Show » 208 23.4 Yes 0
FGF10-002 ENSP00000426406
ENST00000513107
D6RG33
Show all »
Show » Show » 66 7 Yes 0