MNT

GENE INFORMATION

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Gene name

MNT (HGNC Symbol)

Synonyms

bHLHd3, MAD6, MXD6, ROX

Description

MAX network transcriptional repressor (HGNC Symbol)

Entrez gene summary

The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

p13.3

Chromosome location (bp)

2384060 - 2401118

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000070444 (version 78.38)

Entrez gene

4335

UniProt

Q99583 (UniProt - Evidence at protein level)

neXtProt

NX_Q99583

Antibodypedia

MNT antibodies
 

PROTEIN VIEW

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MNT-001
 
MNT-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MNT-001 ENSP00000174618
ENST00000174618
Q99583
Show all »
Show » Show » 582 62.3 No 0
MNT-006 ENSP00000476269
ENST00000575394
V9GY02
Show all »
Show » 33 3.8 No 0