MGAT4A

GENE INFORMATION

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Gene name

MGAT4A (HGNC Symbol)

Synonyms

GnT-4a, GnT-Iva

Description

Mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A (HGNC Symbol)

Entrez gene summary

This gene encodes a key glycosyltransferase that regulates the formation of tri- and multiantennary branching structures in the Golgi apparatus. The encoded protein, in addition to the related isoenzyme B, catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc in a beta-1,4 linkage to the Man-alpha-1,3-Man-beta-1,4-GlcNAc arm of R-Man-alpha-1,6(GlcNAc-beta-1,2-Man-alpha-1,3)Man-beta-1,4-GlcNAc-beta-1,4-GlcNAc-beta-1-Asn. The encoded protein may play a role in regulating the availability of serum glycoproteins, oncogenesis, and differentiation. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q11.2

Chromosome location (bp)

98619106 - 98731126

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000071073 (version 78.38)

Entrez gene

11320

UniProt

Q9UM21 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UM21

Antibodypedia

MGAT4A antibodies
 

PROTEIN VIEW

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MGAT4A-001
 
MGAT4A-002
 
MGAT4A-006
 
MGAT4A-201
 
MGAT4A-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MGAT4A-001 ENSP00000264968
ENST00000264968
Q9UM21
Show all »
Show » Show » 535 61.5 Yes 0
MGAT4A-002 ENSP00000386841
ENST00000409391
Q9UM21
Show all »
Show » Show » 535 61.5 Yes 0
MGAT4A-006 ENSP00000475198
ENST00000495056
U3KPT4
Show all »
Show » Show » 44 5.1 Yes 0
MGAT4A-201 ENSP00000377127
ENST00000393487
Q9UM21
Show all »
Show » Show » 535 61.5 Yes 0
MGAT4A-202 ENSP00000404889
ENST00000414521
Q9UM21
Show all »
Show » Show » 423 48.9 No 0