FCGR2B

GENE INFORMATION

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Gene name

FCGR2B (HGNC Symbol)

Synonyms

CD32, CD32B, FCG2, FCGR2

Description

Fc fragment of IgG, low affinity IIb, receptor (CD32) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

Chromosome

1

Cytoband

q23.3

Chromosome location (bp)

161581311 - 161678654

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000072694 (version 78.38)

Entrez gene

2213

UniProt

P31994 (UniProt - Evidence at protein level)

neXtProt

NX_P31994

Antibodypedia

FCGR2B antibodies
 

PROTEIN VIEW

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FCGR2B-001
 
FCGR2B-002
 
FCGR2B-005
 
FCGR2B-201
 
FCGR2B-202
 
FCGR2B-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FCGR2B-001 ENSP00000356938
ENST00000367961
P31994
Show all »
Show » Show » 303 33.4 No 1
FCGR2B-002 ENSP00000351497
ENST00000358671
P31994
Show all »
Show » Show » 310 34 Yes 1
FCGR2B-005 ENSP00000236937
ENST00000236937
P31994
Show all »
Show » Show » 291 31.9 Yes 1
FCGR2B-201 ENSP00000356937
ENST00000367960
P31994
Show all »
Show » Show » 303 33.4 No 1
FCGR2B-202 ENSP00000386038
ENST00000403078
P31994
Show all »
Show » Show » 291 31.9 Yes 1
FCGR2B-203 ENSP00000404329
ENST00000428605
P31994
Show all »
Show » Show » 310 34 Yes 1