DHRS9

GENE INFORMATION

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Gene name

DHRS9 (HGNC Symbol)

Synonyms

3alpha-HSD, RDH15, RDHL, RETSDR8, SDR9C4

Description

Dehydrogenase/reductase (SDR family) member 9 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Chromosome

2

Cytoband

q31.1

Chromosome location (bp)

169064789 - 169096167

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000073737 (version 78.38)

Entrez gene

10170

UniProt

Q9BPW9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BPW9

Antibodypedia

DHRS9 antibodies
 

PROTEIN VIEW

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DHRS9-001
 
DHRS9-002
 
DHRS9-004
 
DHRS9-005
 
DHRS9-006
 
DHRS9-008
 
DHRS9-201
 
DHRS9-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DHRS9-001 ENSP00000350154
ENST00000357546
Q9BPW9
Show all »
Show » Show » 319 35.2 Yes 0
DHRS9-002 ENSP00000473337
ENST00000602501
Q9BPW9
Show all »
Show » Show » 319 35.2 Yes 0
DHRS9-004 ENSP00000407167
ENST00000436483
Q9BPW9
Show all »
Show » Show » 319 35.2 Yes 0
DHRS9-005 ENSP00000388564
ENST00000428522
Q9BPW9
Show all »
Show » Show » 319 35.2 Yes 0
DHRS9-006 ENSP00000391214
ENST00000450153
C9J430
Show all »
Show » 66 7.3 Yes 0
DHRS9-008 ENSP00000388066
ENST00000421653
Q9BPW9
Show all »
Show » Show » 172 18.9 No 0
DHRS9-201 ENSP00000407747
ENST00000412271
Q9BPW9
Show all »
Show » Show » 319 35.2 Yes 0
DHRS9-202 ENSP00000389241
ENST00000432060
Q9BPW9
Show all »
Show » Show » 379 41.9 No 1